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Choline is necessary for synthesis associated with the neurotransmitter acetylcholine and of the choline-containing phospholipids PC and sphingomyelin (SM) also plays a recently appreciated important role as a methyl donor in the paths of "one-carbon (1C)" metabolic process. This review talks about growing proof that some of the biological features among these intra- and extracellular PLD enzymes include generation of choline with a particular concentrate on the possibility why thes