https://alkgene.com/autophagy-....activated-simply-by-
(p)ppGpp's discussion with an XPRT bridging cycle over the interface leads to XPRT cooperatively binding (p)ppGpp. Additionally, XPRT shows differential regulation because of the alarmones since it is potently inhibited by both ppGpp and pGpp, but only modestly by pppGpp. Lastly, we prove that the alarmones are necessary for protecting GTP homeostasis against excess ecological xanthine in B. subtilis, suggesting that legislation of XPRT is key for controlling t
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