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https://www.selleckchem.com/pr....oducts/cbl0137-cbl-0
Therefore, ABCA1 is the central factor that links cholesterol efflux and apoptotic cell clearance. Several drugs have been studied or approved for apoptotic cell clearance, such as CD47 antibody and PD1-/PD-L1 antibody. In this article, we review the role and mechanism of action of ABCA1 in efferocytosis and focus on new insights into the ABCA1-efferocytosis axis and its potential as a novel therapeutic target in atherosclerosis.ErbB2 (or HER2) is a receptor tyrosine kinase overexpressed in some breast cancers and associated wi