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https://www.selleckchem.com/pr....oducts/tak-243-mln24
n, generating paclitaxel bound fragments that undergo degradation. A new microtubule network forms from tubulins that are not bound by paclitaxel. Hence, ultrasound shock waves are able to abolish paclitaxel impact on microtubules. Thus, our results demonstrate that a brief exposure to low intensity ultrasound can reduce and/or eliminate cytotoxicity associated with paclitaxel treatment of cancer cells in cultures. B vitamins and methionine are essential substrates in the one-carbon metabolism pathway involved in DNA synthesis an