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It was further found that LC-CNS@NTA-treated cells showed reduced level of intracellular protein carbonylation and protein aggregation. The finding of the present study is expected to pave the path for designing engineered metal-free carbon nanozyme with dual enzyme mimic activity.Clustered regularly interspaced palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins, particularly Cas9, have provided unprecedented control on targeting and editing specific DNA sequences. If the target sequences are prone to folding into noncanoni