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To observe the weight change in Chinese youth during a 4-month COVID-19 lockdown, and the association between weight change and mental health, physical activity and sedentary time changes, and dietary habits. A retrospective observational study. Two universities located in Zhejiang and Hunan provinces, China. This study enrolled 12 889 college students whose body weight was measured before the lockdown (1 December 2019-20 January 202 at the two universities, and reported their weight measured at home or community after the end of the