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The future of anti-TGF-β signaling therapy for numerous diseases appears bright, and the outlook for the use of TGF-β inhibitors in cancer radiotherapy as TME-targeting agents is promising.Cases of Multiple sclerosis are being increasingly recognized in Sri Lanka and South Asia challenging the concept of MS being a disease of the West. Our study estimates a crude prevalence of 7.78 cases per 100,000 population in Sri Lanka. They carry a secure diagnosis satisfying the 2017 McDonalds criteria with sero-negativity for AQP4 and MOG antibod
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