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In this note we describe the model, its theoretical bases and discuss its implications. We illustrate the hypotheses that can be derived from the model in two cases of preemptive acclimation based on correlations in the environment the shade avoidance response and acclimation to drought. Older women have faced significant disruptions in social connections during the coronavirus disease 2019 pandemic. Whether loneliness increased, or whether a change in loneliness from pre- to intra-pandemic period was associated with mental health durin