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In addition, curcumin supplementation showed significant improvement in oxidative stress, apoptosis and immune dysfunction, but the improved effect gradually weakened during the exposure last. Gas chromatography-mass spectrometry (GC-MS) analysis for accumulation of CPF in muscle supported the changes of general physiological structure, excessive apoptotic responses, abnormal antioxidant and immune system functions and posed potential human health risks to children based on target hazard quotient. These results suggested that chronic e