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During the coronavirus disease 2019 (COVID-19) pandemic the use of Indirect calorimetry (IC) during nutritional rehabilitation program requires special precautions due to possible contagions for patients and health professionals. We evaluated in a sample of healthy subjects the agreement between oxygen consumption (VO mL/min), carbon dioxide production (VCO mL/min), respiratory quotient (RQ) and resting energy expenditure (REE kcal/24h/day) measured by IC with and without a filtering facepiece mask. 10 subjects with a mean (SD) age of 4