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Novel sandwich-structured carriers were developed for fast immobilizing anammox sludge, with which a fixed-film membrane bioreactor was further established for treating municipal wastewater. Results showed that fast start-up of the fixed-film reactor with anammox bacteria could be achieved without lag phase, indicated by the respective nitrogen removal efficiency and rate of 70.58 ± 0.66% and 0.12 g N/(L·d). Meanwhile, low membrane fouling 0.0017 bar/hour was also observed. The activity of anammox sludge fixed in the novel carriers grad