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In this study, we try to investigate the consequences of two stingless bee (SL propolis from Tetragonula laeviceps and Tetrigona melanoleuca against cellular wall-associated melanin in C. neoformans, as well as its protected reaction in RAW 264.7 macrophage. The ethanolic plant of SLB propolis (EEP) has highly exhibited anti-cryptococcal task. Furthermore, EEP from both sources paid off chitin/chitosan and melanin production against C. neoformans in a dose-depende