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Collision induced dissociation experiments revealed that the addition of a modifier significantly delays the droplet evaporation and ion release process. This indicates that the droplet takes up the gas phase modifier to a certain extent (accommodation). Depending on the modifier's properties either charge depletion or retention may eventually be promoted.Cold collisions serve as a sensitive probe of the interaction potential. In the recent study of Klein et al. (Nature Phys. 2017, 13, 35-38), the one-parameter scaling of the interaction