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Some studies reported the chemical content and antimicrobial properties of L. (Lamiaceae), relevant to the ecological variations in some areas of Egypt and other countries, yet no research was conducted on the plant cultivated in the central delta region of Egypt. Also, no previous data reported on inhibition of β-lactamases by To assess β-lactamases inhibition by extracts and the individual constituents. Dried aerial parts of were extracted by hydrodistillation for preparation of essential oil and by methanol for non-volatile constituen