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Increased appetite and better sleep, which categorized as grade 1 adverse event was reported after treatment with AS201-01 tablet. The outcome supports our previous observation that the AS201-01 tablet, given twice a day for 4 days, is safe and nontoxic. The outcome supports our previous observation that the AS201-01 tablet, given twice a day for 4 days, is safe and nontoxic. An increase in the incidence of congenital hypothyroidism (CH) with eutopic gland has been reported worldwide due to neonatal screening programs. In this study, we