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01 ± 0.04 μM) of all compounds tested and the highest SI (21.21 vs. Caco-2 cells). For the LMIT, the diamine 34 showed the highest efficacy, with EC50 values of 2.67 ± 0.08 and 3.02 ± 0.09 μM on the susceptible and resistant isolate of the parasite, respectively.An implicit assumption often made in research on the environmental determinants of health is that the relationships between environmental factors and their health effects are stable over space and time. This is the assumption of stationarity. The health impacts of environmental fac
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