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During the study period 552 patients were admitted to our hospital and met the inclusion criteria. Global mortality in group1 was significantly higher than in group2 (13.8% vs 1.8%; p 0.001). Patients with a sedentary lifestyle had increased COVID-19 mortality independently of other risk factors previously described (hazard ratio 5.91 (1.80-19.41); p = 0.003). A baseline sedentary lifestyle increases the mortality of hospitalized patients with COVID-19. This finding may be of great utility in the prevention of severe COVID-19 disea
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