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This article is devoted to an adaptive tracking control problem for nonlinear systems with input deadzone and saturation, whose virtual control coefficients include the known and unknown terms. A novel smooth function is first introduced to approximate the input nonlinearities. By utilizing an auxiliary variable and the Nussbaum gain technique, an improved real control signal is constructed to handle the uncertainties of the virtual control coefficients and input nonlinearities. Furthermore, an adaptive tracking controller is constru