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The area under the curve for duration of gentamicin was 0.772 (%95 CI 0.742-0.804, P=0.0001), sensitivity 59 (%95 CI 53-65), specificity 82 (%95 CI 78-88), with a cut-off day for duration of gentamicin 7 days. In our study, it was found that ductal contraction decreased and hsPDA rate increased as the rate and duration of gentamicin increased. In our study, it was found that ductal contraction decreased and hsPDA rate increased as the rate and duration of gentamicin increased. Assessing analgesic drugs developed over preceding 50 years