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Epiretinal membrane is a common macular pathology known to cause morphologic changes observed on macular optical coherence tomography (OCT) and retinal nerve fiber layer (RNFL) OCT. However, the longitudinal effect of epiretinal membrane progression on RNFL OCT morphology is not well studied. This report documents a case of epiretinal membrane progression with associated quantifiable changes to the RNFL OCT over time. A 63-year-old man initially presented in 2014 with a grade 0 epiretinal membrane in his left eye and low suspicion of g