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RESULTS Without employing catalyst, these reactions have low yield and busy mixture. The synthesis of compound 4a as sample reaction have alike yield in the presence of ZnO-NPs and Fe3O4 MNPs (entry 20 and entry 3 but removal of catalyst from the mixture of reaction after completing of reaction is comfortable in present of Fe3O4 MNPs. Structures of 4a-4i are confirmed by IR, 1H NMR, 13C NMR mass spectra. CONCLUSION In conclusion, the reaction of α-bromo ketones, isothiocyanate and sodium hydride in the presence of catalytic amount of