https://www.selleckchem.com/pr....oducts/pf-06650833.h
However, 3PTP evoked significant cardio-protections against I/R injury, characterized by the increased +dp/dt value and the decreased elevated LVEDP, erythrocyte extravasation, leukocyte and macrophage/monocyte infiltration, G-CSF expression, poly(ADP-ribose) polymerase 1 expression, TUNEL-positive cells, fragmentation and infarct area. In addition, 3PTP increased Hsp-70 and Bag3 expression and decreased Bax/Bcl-2 ratio, but did not affect Beclin-1 and LC3-II/LC3-I ratio in the heart with I/R injury. CONCLUSIONS 3PTP therapies may t
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