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https://nkl22.com/genomic-char....acterization-of-meth
Modulating the abundance associated with the blood-brain buffer (BB efflux transporter cancer of the breast resistance protein (BCRP) has the potential to impact brain levels of drugs and endogenous substrates. Studies have shown that the metal ionophore clioquinol (CQ) increases BBB abundance of P-glycoprotein (P-gp), an effect related to increased endothelial cell levels of Cu2+. This research therefore evaluated w