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Crucial QoL effects were mean modifications from standard and time for you to deterioration in QoL. A post hoc evaluation assessed the organization between QoL and time for you deterioration of Eastern Cooperative Oncology Group performance score (ECOG PS) to ≥ 2. RESULTS Of 507 randomized patients, 496 had standard QoL data available. The evaluation cut-off was 6 cycles for trifluridine/tipiracil and 3 cycles for placebo. Both in treatment groups, there have bee