https://www.selleckchem.com/pr....oducts/abtl-0812.htm
Finally, whereas RNA-seq and ChIP-seq showed no concomitant changes in chromatin methylation or gene expression in Setd2SRI/wt mice, primary neurons exhibited structural deficits in axon length and dendritic arborization. These data provide the first demonstration microtubules of neurons are methylated, and reveals a heterozygous chromatin remodeler defect that specifically disables microtubule methylation is sufficient to drive an autism-associated phenotype.In non-alcoholic steatohepatitis (NASH), decreased nitric oxide and increase
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