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To investigate if single-nucleotide polymorphisms (SNPs) in the gene encoding contribute to the development of type-2 diabetes mellitus (T2DM) and whether genotypes of two polymorphisms, rs28514894 and rs2303044, are associated with laboratory characteristics of T2DM patients. A total of 900 subjects (450 T2DM cases and 450 healthy subjects) of Iranian ancestry were genotyped for polymorphisms via ARMS-PCR and PCR-RFLP techniques. Our findings showed a significant correlation between both polymorphisms and increased risk of T2DM. The hap
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