https://www.selleckchem.com/
Interestingly, cells infected with herpes simplex virus type-1 (HSV-1) incorporated EdC and EdU at similar levels during short pulses. Of note, exogenous expression of HSV-1 thymidine kinase (TK) increased the incorporation efficiency of EdC. These results highlight the limitations when using substituted pyrimidine analogs in pulse-labeling and suggest that EdU is the preferable nucleoside analog for short pulse-labeling experiments, resulting in increased recovery and sensitivity for downstream applications. This is an important discovery that may help to
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