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All legal rights reserved.Glucose is considered the most abundant monosaccharide, and a vital energy source for most residing cells. Glucose transport across the cell membrane layer is mediated by 2 kinds of transporters facilitative sugar transporters (GLUTs, gene name solute-carrier (SLC)2A) and sodium glucose co-transporters (SGLTs, gene name SLC5A). Each transporter possesses its own substrate specificity, circulation, and regulatory systems. Recently, sodium sugar co-t