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001), UrRBP/Cr (p 0.001) and UrNAG/Cr (p 0.001) than group B. In group A, microalbuminuria was detected only in 7 patients (28%) while it was detected in 12 patients (33.3%) in group B. By using ROC curve analysis, the diagnostic cutoff values for UrNGAL/Cr, UrRBP/Cr and UrNAG/Cr were 3713.38, 1614.85 and 56.56 ng/g, respectively. We found a statistically significant superiority of UrNGAL/Cr over UrRBP/Cr (p 0.001) and UrRBP/Cr over UrNAG/Cr (p 0.001). Evaluation of UrNGAL/Cr, UrRBP/Cr and UrNAG/Cr could early discrim