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Conclusion Crude polysaccharides extracted from G. lucidum showed a hepatoprotective effect, regenerating damaged liver tissue. Copyright © Susilo, et al.Aim The present study was designed for the detection of the most prevalent respiratory infections in chicken flocks and clarifying their interaction and impact on flock health. Materials and Methods A total of 359 serum samples were collected from 55 backyard chickens and tested using commercial enzyme-linked immunosorbent assay kits to determine the seroprevalence of Newcastle diseas