https://www.selleckchem.com/products/cx-5461.html
Mutations in ATP1A2, the gene encoding the α2 subunit of Na /K -ATPase, are the main cause of familial hemiplegic migraine type 2 (FHM2). The clinical presentation of FHM2 with mutations in the same gene varies from pure FHM to severe forms with epilepsy and intellectual disability, but the correlation of these symptoms with different ATP1A2 mutations is still unclear. Ten ATP1A2 missense mutations were selected according to different phenotypes of FHM patients. They caused pure FHM (FHM R65W, R202Q, R593W, G762S), FHM with epilepsy (FH
Like
Comment
Share
