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Awareness of MIS-C coexistence with DKA at T1DM onset is crucial for rapid proper management. Awareness of MIS-C coexistence with DKA at T1DM onset is crucial for rapid proper management.To date, identification of nonislet-specific transcriptional factors in the regulation of insulin gene expression has been little studied. Here, we report that the expression level of the transcription factor YY1 is increased dramatically in both human and mouse pancreatic β-cells after birth. Nevertheless, the physiological role of YY1 during β-cell dev