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Breg-mediated protection against MI was abrogated by treatment with an interleukin 10 (IL-1 antibody. Finally, IL-10 neutralization reversed the effect of Bregs on monocyte migration and CCR2 expression. The present study suggests a therapeutic value of Bregs in limiting ventricular remodeling after MI through decreasing CCR2-mediated monocyte recruitment and mobilization. Evaluate the need for re-intervention on dental coronal restorations in adults seen in a network of generaldental practitioners (ReCOL). MATERIALS AND METHODS This