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As well as entire flowers, hairy roots (HR) cultures can be used, representing a manifestation system very easy to build up, with long development while handled under containment circumstances. Leads to this study manufacturing in HR of a recombinant antibody, turned out to be good candidate for human immunotherapy against fungal attacks, is reported. Expression and secretion with this antibody, in an engineered solitary sequence (scFvFc) structure, by HR from Nicotiana benthamiana and Solanum lycop