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Regardless of the effects on lifespan, Aβ42 peptide treatment induced decrease in AMP genes expression in females, but the effects were not robust. The results demonstrate that chronic treatment with Aβ42 peptides does not drastically affect fly aging or immunity. The results demonstrate that chronic treatment with Aβ42 peptides does not drastically affect fly aging or immunity. Previous studies have shown catabolism of adenosine 5'-triphosphate (ATP) in systemic blood is a potential surrogate biomarker for cardiovascular toxicity. We c