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https://www.selleckchem.com/pr....oducts/s-adenosyl-l-
Magnetic resonance imaging (MRI) measures may be used as outcome markers in frontotemporal dementia (FTD). To predict MRI cortical thickness (CT) at follow-up at the single subject level, using brain MRI acquired at baseline in preclinical FTD. 84 presymptomatic subjects carrying Granulin mutations underwent MRI scans at baseline and at follow-up (31.2±16.5 months). Multivariate nonlinear mixed-effects model was used for estimating individualized CT at follow-up based on baseline MRI data. The automated user-friendly p