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He was then treated with nivolumab in second-line setting and practiced a rapid improvement of cancer-related symptoms, total remission of leptomeningeal and lung lesions, and increased bone tissue mineral density in bone tissue metastasis. The patient would not experience any drug-related toxicity. CONCLUSIONS Meningeal carcinomatosis metastasis from renal cancer is a rare problem. Diagnosis can be challenging the start of nonspecific presenting signs might be initially attributed to bone tissue involv
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