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Some hormonal and targeted treatment options are available in the first line of metastatic HR+ HER2- breast cancer. This study aimed to quantify the preferences of Iranian breast cancer patients regarding the levels of attributes of hypothetical treatment options. The discrete choice experiment included 16 orthogonally designed scenarios. A novel method (named "the World Cup" was used to offer the scenarios to the respondents. Each choice task had 2 hypothetical treatments. A conditional logit regression model was used to obtain p