https://www.selleckchem.com/pr....oducts/LY2603618-IC-
Our data indicate that GrA+ Th cells represent a distinct Th subset and are critical mediators of aGVHD.Interstitial cells of Cajal (ICCs) are pacemaker cells in the intestine, and their function can be compromised by loss of C-KIT expression. Macrophage activation has been identified in intestine affected by Hirschsprung disease-associated enterocolitis (HAEC). In this study, we examined proinflammatory macrophage activation and explored the mechanisms by which it downregulates C-KIT expression in ICCs in colon affected by HAEC
Like
Comment
Share
