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https://www.selleckchem.com/pr....oducts/Decitabine.ht
In vivo data demonstrate that YdiU effectively protects Salmonella from stress-induced ATP depletion through UMPylation.Cells coordinate interphase-to-mitosis transition, but recurrent cytogenetic lesions appear at common fragile sites (CFSs), termed CFS expression, in a tissue-specific manner after replication stress, marking regions of instability in cancer. Despite such a distinct defect, no model fully provides a molecular explanation for CFSs. We show that CFSs are characterized by impaired chromatin folding, manifesting as disr