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The relationship between ( ) and hepatocellular carcinoma (HCC) was firstly proposed in 1994 after Ward et al demonstrated the role of in the development of HCC in mice. Studies also investigated the role of hepatitis B virus (HBV) and hepatitis C virus (HCV) coexisting with in causing HCC. A causal relationship was never confirmed, and the relationship remains controversial. This meta-analysis aimed to summarize the research on this topic and investigate if a relationship exists between infection and the development of HCC and if the
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