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's formant region, could be vowel dependent. Strategies to control valleculae volumes are likely to be highly relevant to voice pedagogy practice as well as singing performance.Nuclear receptors are ligand-activated transcription factors that can modulated cellular processes involved in the development, homeostasis, cell proliferation, metabolism, and reproduction through the control of the specific genetic and molecular program. In the central nervous system, they are key regulators of neural stem cell fate decisions and can modulate t