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omeostasis. Early-phase bioluminescence imaging of luciferase-expressing islets could serve as a useful tool to predict the success of subcutaneous islet transplantations by preceding changes in glucose homeostasis. The nature in which health care insurance companies have interacted with drug manufacturers has evolved over the last 50years, demanding shifts in how the pharmaceutical industry responds. The purpose of this article is to highlight how medical groups within Pharma Collaboration for Transparent Medical Information (phactMI™