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The latter effect was more pronounced in 3D compared to 2D cell culture. Herein, we described a long-term glioblastoma 3D model system that could be particularly helpful for drug testing and treatment optimization. Herein, we described a long-term glioblastoma 3D model system that could be particularly helpful for drug testing and treatment optimization.The risk of accidents while operating a drone is quite high. The most important solution is training for drone pilots. Drone pilot training can be done in both physical and virtual envir