https://www.selleckchem.com/pe....ptide/pki-14-22-amid
Length of poly IC molecule also influence IFNβ expression in response of RLR pathway. Short (LMW) poly IC induce stronger IFN-β expression in myeloid (macrophage and monocyte) cells. In contrast long (HMW) poly IC preferably elicit higher IFNβ expression in non-myeloid (fibroblast) cell. Therefore, MDA5 and RIG-1 plays an indispensable role in eliciting antiviral response in non- immune (fibroblast) host cell. Thus, stimulation of RLR pathway with suitable and potentially cell-type specific agonist molecules success
Like
Comment
Share
