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54 to 0.74), and five Laws' filter features were correlated with TOLLIP-2 (rs5743905) mutations (AUC 0.53 to 0.7. None of the features analyzed were found to be correlated with MUC5B mutations. First-order and fractal features demonstrated the greatest discrimination between KM curves. Conclusions A radiomics approach for the correlation of patient genetic mutations with image texture features has potential as a biomarker. These features also may serve as prognostic indicators using a survival curve modeling approach in which the combination of radiomic f