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Satisfactory relative recoveries of 94.5-103.5% were obtained, implying method reliability. Overall, the proposed method provides good accuracy and repeatability, high reusability, and good applicability to determine antifungal drugs in complex biological matrices.We developed peptide probes containing a non-hydrolyzable phosphotyrosine mimetic, 4-[difluorphosphono)methyl]-L-phenylalanine (F2 Pmp) for enrichment of protein tyrosine phosphatases (PTPs). We found that different F2 Pmp probes can enrich different PTPs, depending on the p
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