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This links BLVR-A activity to cell growth and survival pathways. BLVR-A also contains a bZip DNA binding domain and a nuclear export sequence (NES) and acts as a transcription factor to regulate the expression of immune modulatory genes. Here we will discuss the role of heme-related immune response and the potential for targeting the heme system for therapies directed toward hepatitis and cancer. Copyright © 2020 Canesin, Hejazi, Swanson and Wegiel.Drosophila hemocytes, like those of mammals, are given rise from two distincti