https://www.selleckchem.com/pr....oducts/AZD2281(Olapa
Overall, this approach led to the identification of four molecules involved in PV IgG-induced skin pathology MEK1, TrkA, PI3Kα, and VEGFR2. This unbiased screening revealed novel mechanisms by which PV autoantibodies induce blistering in keratinocytes and identified new treatment targets for this severe and potentially life-threatening skin disease. This unbiased screening revealed novel mechanisms by which PV autoantibodies induce blistering in keratinocytes and identified new treatment targets for this severe and potentially
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