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https://www.selleckchem.com/pr....oducts/grazoprevir.h
Compared with HCs, patients had TIcolon ratios higher for TA contrast (p0.001), decreased TI motility (lower mean motility [p=0.04], spatial motility variation [p=0.03], and area of motile TI [p=0.03]), and increased ACD (p=0.001). IBS-C and FABD patients show reduced TI motility and differences in luminal content compared with HCs. This potentially indicates reflux of colonic contents or delayed clearance of the TI, which alongside increased ACD may contribute to symptoms of constipation and bloating. IBS-C and FABD patients sh